K75N (p.Lys75Asn) variant of AURKA (Aurora kinase A)
K75N (p.Lys75Asn) in AURKA (Aurora kinase A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
K75N (p.Lys75Asn) variant details
- p.Lys75Asn
- gnomAD rs1163949591
- Missense
- Variant Prioritization Score for Impact Estimate 0.151
- REVEL 0.04
- CADD 12.70
- PolyPhen-2 0.01
- SIFT 0.33
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available