G21D (p.Gly21Asp) variant of AURKA (Aurora kinase A)
G21D (p.Gly21Asp) in AURKA (Aurora kinase A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
G21D (p.Gly21Asp) variant details
- p.Gly21Asp
- TOPMed rs1422893955
- gnomAD rs1422893955
- Missense
- Variant Prioritization Score for Impact Estimate 0.286
- REVEL 0.11
- CADD 17.70
- PolyPhen-2 0.42
- SIFT 0.03
- Most common in the Latino/Admixed American population (allele frequency 4.5e-05)
- Structural context available