F31V (p.Phe31Val) variant of AURKA (Aurora kinase A)
F31V (p.Phe31Val) in AURKA (Aurora kinase A) is a missense change. Clinical records from EBI and UniProt describe it as benign. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data and structural context.
F31V (p.Phe31Val) variant details
- p.Phe31Val
- 1000Genomes rs2273535
- ESP rs2273535
- ExAC rs2273535
- TOPMed rs2273535
- Benign
- Missense
- Variant Prioritization Score for Impact Estimate 0.0744
- REVEL 0.07
- CADD 1.39
- PolyPhen-2 0.00
- SIFT 0.50
- EBI: Benign (in dbSNP:rs2273535)
- UniProt: Benign (in dbSNP:rs2273535)
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available