G59W (p.Gly59Trp) variant of ATP13A2 (Q9NQ11)
G59W (p.Gly59Trp) in ATP13A2 (Q9NQ11) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data and structural context.
G59W (p.Gly59Trp) variant details
- p.Gly59Trp
- gnomAD rs1463031705
- Missense
- Variant Prioritization Score for Impact Estimate 0.609
- REVEL 0.48
- CADD 27.30
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available