V25M (p.Val25Met) variant of APOL1 (Apolipoprotein L1)
V25M (p.Val25Met) in APOL1 (Apolipoprotein L1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
V25M (p.Val25Met) variant details
- p.Val25Met
- TOPMed rs1300964795
- gnomAD rs1300964795
- Missense
- Variant Prioritization Score for Impact Estimate 0.231
- REVEL 0.08
- CADD 13.90
- PolyPhen-2 0.20
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available