V23M (p.Val23Met) variant of APOL1 (Apolipoprotein L1)
V23M (p.Val23Met) in APOL1 (Apolipoprotein L1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
V23M (p.Val23Met) variant details
- p.Val23Met
- TOPMed rs1439034159
- gnomAD rs1439034159
- Missense
- Variant Prioritization Score for Impact Estimate 0.195
- REVEL 0.15
- CADD 17.10
- PolyPhen-2 0.34
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available