T42A (p.Thr42Ala) variant of APOL1 (Apolipoprotein L1)
T42A (p.Thr42Ala) in APOL1 (Apolipoprotein L1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
T42A (p.Thr42Ala) variant details
- p.Thr42Ala
- TOPMed rs2015917535
- Missense
- Variant Prioritization Score for Impact Estimate 0.121
- REVEL 0.07
- CADD 4.16
- PolyPhen-2 0.07
- SIFT 0.12
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available