S17G (p.Ser17Gly) variant of APOL1 (Apolipoprotein L1)
S17G (p.Ser17Gly) in APOL1 (Apolipoprotein L1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data, published literature, and structural context.
S17G (p.Ser17Gly) variant details
- p.Ser17Gly
- gnomAD 22-36257087-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.0749
- REVEL 0.04
- MetaLR 0.03
- MetaSVM -1.06
- CADD 0.38
- PolyPhen-2 0.00
- SIFT 0.30
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available
- Literature evidence available