S10C (p.Ser10Cys) variant of APOL1 (Apolipoprotein L1)
S10C (p.Ser10Cys) in APOL1 (Apolipoprotein L1) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data, published literature, and structural context.
S10C (p.Ser10Cys) variant details
- p.Ser10Cys
- gnomAD 22-36254980-GTC-G
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.209
- CADD 18.10
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available