R8W (p.Arg8Trp) variant of APOL1 (Apolipoprotein L1)
R8W (p.Arg8Trp) in APOL1 (Apolipoprotein L1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data, published literature, and structural context.
R8W (p.Arg8Trp) variant details
- p.Arg8Trp
- gnomAD 22-36254899-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.363
- CADD 8.69
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available