R33G (p.Arg33Gly) variant of APOL1 (Apolipoprotein L1)
R33G (p.Arg33Gly) in APOL1 (Apolipoprotein L1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
R33G (p.Arg33Gly) variant details
- p.Arg33Gly
- ExAC rs778581142
- gnomAD rs778581142
- Missense
- Variant Prioritization Score for Impact Estimate 0.12
- REVEL 0.08
- CADD 14.00
- PolyPhen-2 0.23
- SIFT 0.20
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available