R26K (p.Arg26Lys) variant of APOL1 (Apolipoprotein L1)
R26K (p.Arg26Lys) in APOL1 (Apolipoprotein L1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
R26K (p.Arg26Lys) variant details
- p.Arg26Lys
- TOPMed rs1247964955
- gnomAD rs1247964955
- Missense
- Variant Prioritization Score for Impact Estimate 0.34
- REVEL 0.04
- CADD 16.40
- PolyPhen-2 0.64
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available