P51A (p.Pro51Ala) variant of APOL1 (Apolipoprotein L1)
P51A (p.Pro51Ala) in APOL1 (Apolipoprotein L1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data, published literature, and structural context.
P51A (p.Pro51Ala) variant details
- p.Pro51Ala
- gnomAD 22-36257371-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.0826
- REVEL 0.05
- MetaLR 0.03
- MetaSVM -1.03
- CADD 1.16
- PolyPhen-2 0.00
- SIFT 0.23
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available