L7R (p.Leu7Arg) variant of APOL1 (Apolipoprotein L1)
L7R (p.Leu7Arg) in APOL1 (Apolipoprotein L1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
L7R (p.Leu7Arg) variant details
- p.Leu7Arg
- Ensembl rs1556624040
- Missense
- Variant Prioritization Score for Impact Estimate 0.219
- REVEL 0.10
- CADD 20.50
- PolyPhen-2 0.59
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available