L7P (p.Leu7Pro) variant of APOL1 (Apolipoprotein L1)
L7P (p.Leu7Pro) in APOL1 (Apolipoprotein L1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
L7P (p.Leu7Pro) variant details
- p.Leu7Pro
- Ensembl rs1556624040
- Missense
- Variant Prioritization Score for Impact Estimate 0.238
- REVEL 0.13
- CADD 20.90
- PolyPhen-2 0.59
- SIFT 0.00
- Most common in the East Asian population (allele frequency 5e-05)
- Structural context available