L12P (p.Leu12Pro) variant of APOL1 (Apolipoprotein L1)
L12P (p.Leu12Pro) in APOL1 (Apolipoprotein L1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
L12P (p.Leu12Pro) variant details
- p.Leu12Pro
- gnomAD rs1398634941
- Missense
- Variant Prioritization Score for Impact Estimate 0.174
- REVEL 0.20
- CADD 12.00
- PolyPhen-2 0.00
- SIFT 0.00
- Most common in the South Asian population (allele frequency 7e-05)
- Structural context available