K50E (p.Lys50Glu) variant of APOL1 (Apolipoprotein L1)
K50E (p.Lys50Glu) in APOL1 (Apolipoprotein L1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data and structural context.
K50E (p.Lys50Glu) variant details
- p.Lys50Glu
- TOPMed rs2015918869
- Missense
- Variant Prioritization Score for Impact Estimate 0.0569
- REVEL 0.03
- CADD 3.96
- PolyPhen-2 0.22
- SIFT 0.22
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available