I14T (p.Ile14Thr) variant of APOL1 (Apolipoprotein L1)
I14T (p.Ile14Thr) in APOL1 (Apolipoprotein L1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, published literature, and structural context.
I14T (p.Ile14Thr) variant details
- p.Ile14Thr
- gnomAD 22-36254996-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.142
- REVEL 0.09
- MetaLR 0.04
- MetaSVM -1.04
- CADD 15.90
- PolyPhen-2 0.10
- SIFT 0.04
- Population evidence available
- Structural context available
- Literature evidence available