G31R (p.Gly31Arg) variant of APOL1 (Apolipoprotein L1)
G31R (p.Gly31Arg) in APOL1 (Apolipoprotein L1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
G31R (p.Gly31Arg) variant details
- p.Gly31Arg
- gnomAD rs1336821136
- Missense
- Variant Prioritization Score for Impact Estimate 0.186
- REVEL 0.10
- CADD 16.10
- PolyPhen-2 0.13
- SIFT 0.01
- Most common in the South Asian population (allele frequency 3.5e-05)
- Structural context available