G31A (p.Gly31Ala) variant of APOL1 (Apolipoprotein L1)
G31A (p.Gly31Ala) in APOL1 (Apolipoprotein L1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
G31A (p.Gly31Ala) variant details
- p.Gly31Ala
- TOPMed rs2015908447
- Missense
- Variant Prioritization Score for Impact Estimate 0.0761
- REVEL 0.06
- CADD 3.74
- PolyPhen-2 0.59
- SIFT 0.36
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available