G24E (p.Gly24Glu) variant of APOL1 (Apolipoprotein L1)
G24E (p.Gly24Glu) in APOL1 (Apolipoprotein L1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data, published literature, and structural context.
G24E (p.Gly24Glu) variant details
- p.Gly24Glu
- gnomAD 22-36257109-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.0904
- REVEL 0.06
- MetaLR 0.04
- MetaSVM -1.03
- CADD 0.99
- PolyPhen-2 0.07
- SIFT 0.50
- Most common in the Middle Eastern population (allele frequency 0.00017)
- Structural context available
- Literature evidence available