F20S (p.Phe20Ser) variant of APOL1 (Apolipoprotein L1)
F20S (p.Phe20Ser) in APOL1 (Apolipoprotein L1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
F20S (p.Phe20Ser) variant details
- p.Phe20Ser
- 1000Genomes rs201933483
- TOPMed rs201933483
- gnomAD rs201933483
- Missense
- Variant Prioritization Score for Impact Estimate 0.199
- REVEL 0.23
- CADD 6.09
- PolyPhen-2 0.03
- SIFT 0.05
- Most common in the 1KG:CHS population (allele frequency 0.0049)
- Structural context available