F20L (p.Phe20Leu) variant of APOL1 (Apolipoprotein L1)
F20L (p.Phe20Leu) in APOL1 (Apolipoprotein L1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
F20L (p.Phe20Leu) variant details
- p.Phe20Leu
- TOPMed rs2015906589
- Missense
- Variant Prioritization Score for Impact Estimate 0.101
- REVEL 0.10
- CADD 2.52
- PolyPhen-2 0.02
- SIFT 1.00
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available