A57P (p.Ala57Pro) variant of APOL1 (Apolipoprotein L1)
A57P (p.Ala57Pro) in APOL1 (Apolipoprotein L1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
A57P (p.Ala57Pro) variant details
- p.Ala57Pro
- TOPMed rs1262713437
- Missense
- Variant Prioritization Score for Impact Estimate 0.178
- REVEL 0.07
- CADD 16.50
- PolyPhen-2 0.70
- SIFT 0.25
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available