A4P (p.Ala4Pro) variant of APOL1 (Apolipoprotein L1)
A4P (p.Ala4Pro) in APOL1 (Apolipoprotein L1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
A4P (p.Ala4Pro) variant details
- p.Ala4Pro
- ExAC rs757047440
- TOPMed rs757047440
- gnomAD rs757047440
- Missense
- Variant Prioritization Score for Impact Estimate 0.128
- REVEL 0.09
- CADD 6.53
- PolyPhen-2 0.19
- SIFT 0.12
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available