A4D (p.Ala4Asp) variant of APOL1 (Apolipoprotein L1)
A4D (p.Ala4Asp) in APOL1 (Apolipoprotein L1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
A4D (p.Ala4Asp) variant details
- p.Ala4Asp
- ExAC rs781164721
- TOPMed rs781164721
- gnomAD rs781164721
- Missense
- Variant Prioritization Score for Impact Estimate 0.101
- REVEL 0.13
- CADD 0.33
- PolyPhen-2 0.00
- SIFT 0.34
- Most common in the East Asian population (allele frequency 5e-05)
- Structural context available