A27V (p.Ala27Val) variant of APOL1 (Apolipoprotein L1)
A27V (p.Ala27Val) in APOL1 (Apolipoprotein L1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
A27V (p.Ala27Val) variant details
- p.Ala27Val
- Ensembl rs2015907707
- Missense
- Variant Prioritization Score for Impact Estimate 0.171
- REVEL 0.11
- CADD 12.00
- PolyPhen-2 0.24
- SIFT 0.07
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available