Y75S (p.Tyr75Ser) variant of APOC2 (Apolipoprotein C-II)
Y75S (p.Tyr75Ser) in APOC2 (Apolipoprotein C-II) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data, published literature, and structural context.
Y75S (p.Tyr75Ser) variant details
- p.Tyr75Ser
- gnomAD 19-44949167-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.58
- REVEL 0.73
- CADD 26.40
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available