Y75H (p.Tyr75His) variant of APOC2 (Apolipoprotein C-II)
Y75H (p.Tyr75His) in APOC2 (Apolipoprotein C-II) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.74 / 1. The record also includes population frequency data and structural context.
Y75H (p.Tyr75His) variant details
- p.Tyr75His
- TOPMed rs1339593526
- gnomAD rs1339593526
- Missense
- Variant Prioritization Score for Impact Estimate 0.745
- REVEL 0.81
- CADD 28.90
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available