Y63F (p.Tyr63Phe) variant of APOC2 (Apolipoprotein C-II)
Y63F (p.Tyr63Phe) in APOC2 (Apolipoprotein C-II) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data, published literature, and structural context.
Y63F (p.Tyr63Phe) variant details
- p.Tyr63Phe
- gnomAD 19-44948833-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.465
- REVEL 0.40
- CADD 17.00
- PolyPhen-2 0.56
- SIFT 0.23
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available
- Literature evidence available