T53S (p.Thr53Ser) variant of APOC2 (Apolipoprotein C-II)
T53S (p.Thr53Ser) in APOC2 (Apolipoprotein C-II) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
T53S (p.Thr53Ser) variant details
- p.Thr53Ser
- ExAC rs752909963
- gnomAD rs752909963
- Missense
- Variant Prioritization Score for Impact Estimate 0.146
- REVEL 0.20
- CADD 0.81
- PolyPhen-2 0.01
- SIFT 0.43
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available