F18S (p.Phe18Ser) variant of APOC2 (Apolipoprotein C-II)
F18S (p.Phe18Ser) in APOC2 (Apolipoprotein C-II) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
F18S (p.Phe18Ser) variant details
- p.Phe18Ser
- ExAC rs757247241
- gnomAD rs757247241
- Missense
- Variant Prioritization Score for Impact Estimate 0.182
- REVEL 0.19
- CADD 10.00
- PolyPhen-2 0.00
- SIFT 0.44
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available