D73H (p.Asp73His) variant of APOC2 (Apolipoprotein C-II)
D73H (p.Asp73His) in APOC2 (Apolipoprotein C-II) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.71 / 1. The record also includes population frequency data and structural context.
D73H (p.Asp73His) variant details
- p.Asp73His
- ExAC rs757506929
- gnomAD rs757506929
- Missense
- Variant Prioritization Score for Impact Estimate 0.705
- REVEL 0.73
- CADD 24.90
- PolyPhen-2 0.76
- SIFT 0.08
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available