V102M (p.Val102Met) variant of APOB (Apolipoprotein B-100)
V102M (p.Val102Met) in APOB (Apolipoprotein B-100) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
V102M (p.Val102Met) variant details
- p.Val102Met
- ExAC rs771921277
- gnomAD rs771921277
- Missense
- Variant Prioritization Score for Impact Estimate 0.288
- REVEL 0.15
- MetaLR 0.19
- MetaSVM -0.61
- CADD 22.10
- PolyPhen-2 0.68
- SIFT 0.05
- Most common in the African/African-American population (allele frequency 2.8e-05)
- Structural context available