S89T (p.Ser89Thr) variant of APOB (Apolipoprotein B-100)
S89T (p.Ser89Thr) in APOB (Apolipoprotein B-100) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
S89T (p.Ser89Thr) variant details
- p.Ser89Thr
- TOPMed rs1226992086
- gnomAD rs1226992086
- Missense
- Variant Prioritization Score for Impact Estimate 0.116
- REVEL 0.03
- MetaLR 0.07
- MetaSVM -1.04
- CADD 10.90
- SIFT 0.08
- Most common in the African/African-American population (allele frequency 2.8e-05)
- Structural context available