S89N (p.Ser89Asn) variant of APOB (Apolipoprotein B-100)
S89N (p.Ser89Asn) in APOB (Apolipoprotein B-100) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
S89N (p.Ser89Asn) variant details
- p.Ser89Asn
- TOPMed rs1226992086
- gnomAD rs1226992086
- Missense
- Variant Prioritization Score for Impact Estimate 0.134
- REVEL 0.08
- MetaLR 0.05
- MetaSVM -1.04
- CADD 9.20
- PolyPhen-2 0.01
- SIFT 0.47
- Most common in the 1KG:IBS population (allele frequency 0.017)
- Structural context available