S72G (p.Ser72Gly) variant of APOB (Apolipoprotein B-100)
S72G (p.Ser72Gly) in APOB (Apolipoprotein B-100) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
S72G (p.Ser72Gly) variant details
- p.Ser72Gly
- 1000Genomes rs572869977
- ExAC rs572869977
- gnomAD rs572869977
- Missense
- Variant Prioritization Score for Impact Estimate 0.439
- REVEL 0.40
- MetaLR 0.30
- MetaSVM -0.43
- CADD 28.20
- SIFT 0.00
- Most common in the Ashkenazi Jewish population (allele frequency 7.7e-05)
- Structural context available