S61F (p.Ser61Phe) variant of APOB (Apolipoprotein B-100)
S61F (p.Ser61Phe) in APOB (Apolipoprotein B-100) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
S61F (p.Ser61Phe) variant details
- p.Ser61Phe
- gnomAD rs1323491302
- Missense
- Variant Prioritization Score for Impact Estimate 0.402
- REVEL 0.21
- MetaLR 0.26
- MetaSVM -0.63
- CADD 29.80
- PolyPhen-2 0.94
- SIFT 0.65
- Most common in the South Asian population (allele frequency 0.00044)
- Structural context available