S60N (p.Ser60Asn) variant of APOB (Apolipoprotein B-100)
S60N (p.Ser60Asn) in APOB (Apolipoprotein B-100) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
S60N (p.Ser60Asn) variant details
- p.Ser60Asn
- TOPMed rs1439559056
- gnomAD rs1439559056
- Missense
- Variant Prioritization Score for Impact Estimate 0.3
- REVEL 0.22
- MetaLR 0.24
- MetaSVM -0.43
- CADD 23.20
- PolyPhen-2 0.52
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available