P107T (p.Pro107Thr) variant of APOB (Apolipoprotein B-100)
P107T (p.Pro107Thr) in APOB (Apolipoprotein B-100) is a missense change. Clinical records from EBI and UniProt describe it as benign. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
P107T (p.Pro107Thr) variant details
- p.Pro107Thr
- ExAC rs748863083
- TOPMed rs748863083
- gnomAD rs748863083
- Benign
- Missense
- Variant Prioritization Score for Impact Estimate 0.233
- REVEL 0.03
- MetaLR 0.01
- MetaSVM -0.98
- CADD 11.90
- SIFT 0.37
- EBI: Benign
- UniProt: Benign
- Most common in the Non-Finnish European population (allele frequency 5e-05)
- Structural context available