L9P (p.Leu9Pro) variant of APOB (Apolipoprotein B-100)
L9P (p.Leu9Pro) in APOB (Apolipoprotein B-100) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
L9P (p.Leu9Pro) variant details
- p.Leu9Pro
- 1000Genomes rs1558270119
- Missense
- Variant Prioritization Score for Impact Estimate 0.169
- REVEL 0.17
- MetaLR 0.01
- MetaSVM -0.96
- CADD 13.00
- PolyPhen-2 0.15
- SIFT 0.05
- Most common in the 1KG:GIH population (allele frequency 0.0053)
- Structural context available