L32R (p.Leu32Arg) variant of APOB (Apolipoprotein B-100)
L32R (p.Leu32Arg) in APOB (Apolipoprotein B-100) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
L32R (p.Leu32Arg) variant details
- p.Leu32Arg
- TOPMed rs1350695060
- gnomAD rs1350695060
- Missense
- Variant Prioritization Score for Impact Estimate 0.177
- REVEL 0.16
- MetaLR 0.01
- MetaSVM -0.99
- CADD 13.80
- PolyPhen-2 0.89
- SIFT 0.71
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available