L112W (p.Leu112Trp) variant of APOB (Apolipoprotein B-100)
L112W (p.Leu112Trp) in APOB (Apolipoprotein B-100) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The record also includes variant effect predictions and structural context.
L112W (p.Leu112Trp) variant details
- p.Leu112Trp
- NCI-TCGA Cosmic COSV9926
- cosmic curated COSV99267
- Variant assessed as somatic; moderate impact.
- Missense
- MetaLR 0.20
- MetaSVM -0.55
- SIFT 0.00
- UniProt: Variant assessed as somatic; moderate impact.
- Structural context available