K41E (p.Lys41Glu) variant of APOB (Apolipoprotein B-100)
K41E (p.Lys41Glu) in APOB (Apolipoprotein B-100) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
K41E (p.Lys41Glu) variant details
- p.Lys41Glu
- gnomAD rs1392472584
- Missense
- Variant Prioritization Score for Impact Estimate 0.315
- REVEL 0.05
- MetaLR 0.01
- MetaSVM -0.95
- CADD 18.10
- PolyPhen-2 0.01
- SIFT 0.14
- Most common in the Non-Finnish European population (allele frequency 3.4e-06)
- Structural context available