K117N (p.Lys117Asn) variant of APOB (Apolipoprotein B-100)
K117N (p.Lys117Asn) in APOB (Apolipoprotein B-100) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
K117N (p.Lys117Asn) variant details
- p.Lys117Asn
- Ensembl rs1664117026
- Missense
- Variant Prioritization Score for Impact Estimate 0.326
- REVEL 0.20
- MetaLR 0.23
- MetaSVM -0.53
- CADD 26.30
- PolyPhen-2 0.94
- SIFT 0.06
- Most common in the South Asian population (allele frequency 0.00044)
- Structural context available