K115E (p.Lys115Glu) variant of APOB (Apolipoprotein B-100)
K115E (p.Lys115Glu) in APOB (Apolipoprotein B-100) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
K115E (p.Lys115Glu) variant details
- p.Lys115Glu
- TOPMed rs1235995082
- Missense
- Variant Prioritization Score for Impact Estimate 0.324
- REVEL 0.18
- MetaLR 0.18
- MetaSVM -0.47
- CADD 27.10
- PolyPhen-2 0.84
- SIFT 0.11
- Most common in the HGDP:BIAKA population (allele frequency 0.93)
- Structural context available