G109D (p.Gly109Asp) variant of APOB (Apolipoprotein B-100)
G109D (p.Gly109Asp) in APOB (Apolipoprotein B-100) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data and structural context.
G109D (p.Gly109Asp) variant details
- p.Gly109Asp
- ExAC rs777191260
- gnomAD rs777191260
- Missense
- Variant Prioritization Score for Impact Estimate 0.549
- REVEL 0.45
- MetaLR 0.32
- MetaSVM -0.37
- CADD 26.10
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available