A7T (p.Ala7Thr) variant of APOB (Apolipoprotein B-100)
A7T (p.Ala7Thr) in APOB (Apolipoprotein B-100) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
A7T (p.Ala7Thr) variant details
- p.Ala7Thr
- gnomAD rs1329077757
- Missense
- Variant Prioritization Score for Impact Estimate 0.201
- REVEL 0.02
- MetaLR 0.01
- MetaSVM -0.94
- CADD 18.00
- PolyPhen-2 0.03
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 4.5e-06)
- Structural context available