A58S (p.Ala58Ser) variant of APOB (Apolipoprotein B-100)
A58S (p.Ala58Ser) in APOB (Apolipoprotein B-100) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
A58S (p.Ala58Ser) variant details
- p.Ala58Ser
- gnomAD rs1342403087
- Missense
- Variant Prioritization Score for Impact Estimate 0.441
- REVEL 0.25
- MetaLR 0.26
- MetaSVM -0.50
- CADD 25.60
- PolyPhen-2 0.72
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 5e-05)
- Structural context available