A10T (p.Ala10Thr) variant of APOB (Apolipoprotein B-100)
A10T (p.Ala10Thr) in APOB (Apolipoprotein B-100) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
A10T (p.Ala10Thr) variant details
- p.Ala10Thr
- TOPMed rs1159157996
- Missense
- Variant Prioritization Score for Impact Estimate 0.105
- REVEL 0.01
- MetaLR 0.01
- MetaSVM -0.91
- CADD 4.36
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the African/African-American population (allele frequency 2.8e-05)
- Structural context available